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CAS No.: 56293-29-9

苦豆碱 Catalog No. CSN10253

Synonyms: 苦豆碱;阿洛哌丁

Aloperine is a naturally occuring alkaloid isolated from sophora plants with anti-inflammatory, antibacterial, antiviral, and anti-tumor effect.

规格	价格	促销价格	库存	数量

400-920-2911

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技术信息

生物活性

描述Aloperine, a natural alkaloid isolated from the Chinese traditional herb Sophora alopecuroides, is a broad-spectrum antiviral agent with anti-inflammatory activity. Aloperine effectively inhibited hepatitis C virus (HCV) propagation in Huh7.5 cells and primary human hepatocytes without cytotoxicity, and it blocked HCV cell-to-cell viral transmission. Aloperine additively inhibited HCV propagation with direct-acting antivirals (DAAs) and was effective against HCV variants resistant to known DAAs^[3]. Aloperine exerted the most potent in vitro cytotoxic activity against the human cancer cell lines. Aloperine treatment for 48 hr induced apoptosis in HL-60 cells. In addition, autophagic formation of acidic vacuole was also observed in HL-60 cells exposed to aloperine^[4]. Aloperine significantly inhibited the proliferation and DNA synthesis of human pulmonary artery smooth muscle cells (HPASMCs) induced by platelet-derived growth factor-BB, blocked progression through G0/G1to S phase of the cell cycle and promoted total ratio of apoptosis^[5]. Aloperine (1%) greatly improves the DNFB (2, 4-dinitrofluorobenzene)-induced allergic contact dermatitis in mice^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.3036 mL
- 21.5179 mL
- 43.0358 mL
- 5 mM
- 0.8607 mL
- 4.3036 mL
- 8.6072 mL
- 10 mM
- 0.4304 mL
- 2.1518 mL
- 4.3036 mL

技术信息

CAS号

56293-29-9

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C15H24N2

运输

蓝冰

分子量

232.36

别名

苦豆碱;阿洛哌丁

溶解度

DMSO	44.0 mg/mL (189.4 mM)
Water	44.0 mg/mL (189.4 mM)

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